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French elect mayors in key cities including Paris
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'They beat us with whips': Sudan RSF detainees tell of horrors in El-Fasher
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Australia's Hannah Green wins historic third tournament in a row
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China's premier vows to expand global 'trade pie': state media
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Belgium commemorates Brussels attacks 10 years on
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Sri Lanka raises fuel prices by 25 percent as war bites
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Rights groups fear use of arrest to stifle free speech in Pakistan
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Iranian missiles sow panic, destruction in Israeli towns
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Damaged Russian tanker to be towed to Libya: state-owned company
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Gilgeous-Alexander scores 40, LeBron breaks NBA appearance record
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Cuba hit by second nationwide blackout in a week
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James breaks NBA appearance record as Lakers win thriller
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BTS draws over 100,000 fans to Seoul comeback concert: label
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US-China 'Board of Trade' may help ties but experts flag market worries
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Trump gives Iran 48 hours to open Hormuz as Tehran strikes Israel
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Sinner, defending champ Mensik advance to third round at Miami Open
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Iran missile strikes wound over 100 in two south Israel towns
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Shai hits 40 as Thunder win despite NBA melee with four ejected
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Records shattered as US heatwave moves eastward
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Iran missiles hit southern Israel, injuring more than 100
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LeBron James breaks record for most NBA games played
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'Perfect' PSG sweep past Nice to reclaim top spot in Ligue 1
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Japan coach says Asian Cup crown 'well-deserved' for inspirational team
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PSG sweep past Nice to reclaim top spot in Ligue 1
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Milan move to within five points of Serie A leaders Inter
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Duplantis masterclass as Kerr and record-setter Ehammer shine
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Rosenior urges Chelsea to 'forget the noise' after damaging loss
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Marquez ambushed Di Giannantonio to win Brazil sprint
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Sweden's Duplantis wins fourth world indoor pole vault title
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Iran missile hits Israeli town home to nuclear site after Natanz strike
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Liverpool, Chelsea slip up in Champions League race
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WHO sends first overland convoy from emergencies hub to Beirut
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Everton rub salt in Chelsea wounds as Champions League race tightens
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Coach Mignoni returns but Toulon crash to Stade Francais
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Robert Mueller, ex-FBI chief who led Trump-Russia inquiry, dead at 81
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Sinner and Pegula advance to third round at Miami Open
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Britain's Kerr outsprints Hocker for world indoor 3,000m gold
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Kane backs Tuchel's call to rest him from England friendly
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NBA fines 76ers' Drummond, Magic's Suggs $25,000 each
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Switzerland's Ehammer sets indoor heptathlon world record
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Pogacar 'relieved' by Milan-San Remo triumph, gunning to complete Monument set
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Kenya, Uganda double down on rail extension burdened by Chinese debt
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World Athletics decision to hand Asia two world indoors 'strategic' - Coe
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Trump threatens to use ICE agents for airport security control
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Kane moves closer to goals record as Bayern sink Union
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Pogacar ends long wait for Milan-San Remo glory after edging epic
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Brighton's Welbeck dents Liverpool's Champions League hopes
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US says 'took out' Iran base threatening blocked Hormuz oil route
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Di Giannantonio takes Brazil MotoGP pole ahead of Bezzecchi, Marquez
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Welbeck scores twice to dent Liverpool's top-five hopes
Stocks slide as investors await key Fed speech
Stock markets mostly fell during cautious trading sessions Thursday, a day before a key speech expected to offer signals about future interest rate cuts in the United States.
US Federal Reserve Chairman Jerome Powell, who has resisted President Donald Trump's public demands to slash rates, is scheduled to deliver remarks Friday at the annual central bankers conference in Wyoming.
Major European indices were lower in midday trading, tracking a lacklustre session in Asia, and Wall Street indices opened lower after weakness seen on Wednesday.
Investors largely brushed off purchasing managers' index (PMI) data showing eurozone business activity reached a 15-month high in August, while UK activity grew at its fastest pace in a year.
"Eyes are turning to... Powell's final speech at the Jackson Hole Symposium as Federal Reserve Chair (before his term ends in May 2026)," said Susannah Streeter, head of money and markets at Hargreaves Lansdown.
"Although the effect of Trump's tariffs on monetary policy will be the undercurrent theme, investors will be looking specifically for clues as to the Fed's inclination to cut interest rates," she said.
Data last week provided a mixed picture of US inflation, leaving it uncertain whether the Fed will lower rates as many investors expect in September -- a move that could bolster growth in the world's largest economy.
A recent sell-off in major tech stocks has added to market uncertainty, as investors grow wary of the sustained rally across the sector since April.
The tech-heavy Nasdaq fell again on Thursday, though shares in AI chip designer Nvidia were trading flat after heavy selling in previous sessions ahead of its earnings report next week.
Despite the building unease, shares in Seoul closed higher Thursday, bolstered by an uptick in Samsung's share price.
Shanghai, Sydney and Taipei also saw moderate gains.
Tokyo's Nikkei index closed lower, along with Hong Kong.
Global markets have also fluctuated recently on the prospects of a peace deal in Ukraine, following days of high-stakes diplomacy in the aftermath of Trump's Friday meeting with Russian counterpart Vladimir Putin.
The diplomatic whirlwind has sparked volatility in oil markets as traders speculate over the possible lifting of sanctions on Russia, a major producer.
Oil prices rose again Thursday, following a report the previous day showing a sharp decline in US crude stockpiles.
- Key figures at around 1340 GMT -
New York - Dow: DOWN 0.6 percent at 44,675.02 points
New York - S&P 500: DOWN 0.3 percent at 6,374.53
New York - Nasdaq: DOWN 0.3 percent at 21,116.06
London - FTSE 100: DOWN 0.3 percent at 9,259.45 points
Paris - CAC 40: DOWN 0.6 percent at 7,293.03
Frankfurt - DAX: DOWN 0.2 percent at 24,227.68
Tokyo - Nikkei 225: DOWN 0.7 percent at 42,610.17 (close)
Hong Kong - Hang Seng Index: DOWN 0.2 percent at 25,104.61 (close)
Shanghai - Composite: UP 0.1 percent at 3,770.78 (close)
Euro/dollar: DOWN at $1.1639 from $1.1648 on Wednesday
Pound/dollar: DOWN at $1.3441 from $1.3452
Dollar/yen: UP at 147.64 yen from 147.44 yen
Euro/pound: DOWN at 86.56 pence from 86.59 pence
West Texas Intermediate: UP 0.1 percent at $63.28 per barrel
Brent North Sea Crude: UP 0.1 percent at $66.93 per barrel
S.Leonhard--VB