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South Africa's rooibos heads to space
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Hearts and Scotland keeper Gordon retires
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Climate change, urban growth fuel Lagos flooding
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Ukraine state energy boss Koretsky becomes new PM
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Depleted Italy make nine changes for Australia Test
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UK launches hi-tech mission to study Greenland ice melt
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Peru president-elect Fujimori calls for political 'reconciliation'
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German neo-Nazi sent to male prison despite legal gender change
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UK nationalises struggling British Steel
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Schmidt says struggling Australia 'not far off' as he makes changes for Italy clash
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Italy court to deliver verdict in deadly bridge collapse
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Germany's Delivery Hero agrees 12.7-bn-euro takeover by Uber
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US unveils new 25% tariff on certain imports from Brazil
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Taiwan chipmaker TSMC to invest another US$100 bn in Arizona fabs
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Messi magic sends Argentina into World Cup final as England fall short
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Italy coach Quesada banned for two Tests after TV rant
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Taiwan chipmaker TSMC to invest another $100bn in Arizona fabs
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Climate change, mismanagement dry up beloved Hungarian lake
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Taiwan chipmaker TSMC reports record quarterly profit
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France overhaul front row to face Japan in Nations Championship
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'No rest': Indonesians overworked and abused on foreign fishing vessels
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Next UK PM urged to end Labour Party's 'boys club'
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Actor Sam Neill died of pneumonia, says agent
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No room in All Blacks for Beauden Barrett against Ireland
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Fiji scrum-half Kuruvoli slapped with four-match ban for red card
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Japan give Haangana debut for France 'forward battle' in steamy Tokyo
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Asian stocks mostly sink as AI worries hammer tech
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Ireland coach Farrell relishes another crack at Eden Park record
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'Holding back is evil': Gen-Zers revive Japan's corporate machismo
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Tractors out, oxen in for fuel-starved Cuban farms
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Saving Gaza's past, one artefact at a time
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US bid for Libya reunification a gamble, analysts say
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In Senegal, a feverish ancestral hunt beckons the rain
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Japan to give flanker Haangana his debut against France
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US wants to globalize fight against far-left terrorism
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Messi not done yet after inspiring Argentina to World Cup final
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Familiar tale of woe as England exit World Cup
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Argentina World Cup semi-final hero Martinez 'dreamt' of scoring winner
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'For the Malvinas, for Diego!' World Cup glee takes over in Argentina
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Tuchel defends tactics after England World Cup dream dies
Tepid 2026 outlook dents Pfizer shares
Pfizer signaled Tuesday it expects a challenging 2026 as it invests in new products to offset declines in Covid-19 revenues while limiting shareholder payouts.
Shares of the big drugmaker fell sharply after it projected a dip in full-year adjusted profits per share on roughly flat revenues.
Pfizer expects 2026 revenues of between $59.5 billion and $62.5 billion, compared with $62 billion in 2025.
The pharma giant last month completed an acquisition of biotech firm Metsera, deepening its portfolio of products in the fast-growing market for weight loss drugs.
Pfizer has also identified oncology as a major growth area, while Chief Executive Albert Bourla insisted the company would continue to invest in vaccines in the face of recent controversial policies under the vaccine-skeptic Trump administration.
The drugmaker expects a drop of $1.5 billion in 2026 revenues tied to lower Covid-19 sales and the decline of another $1.5 billion from products experiencing a loss of exclusivity.
Pfizer has maintained a dividend but not undertaken share repurchases in 2025. Executives said they would continue to steer cash into development programs rather than stock repurchases.
"Obviously I would love to do share repurchases," Chief Financial Officer David Denton said on a conference call. "The reality is at this point in time, I think the best and highest use of capital is continued investment in business development."
Briefing.com said the results underscored Pfizer's "painful transition" out of the Covid-19 era.
The tepid outlook "indicates that earnings will likely remain stagnant or decline slightly as the company digests the Metsera deal and ramps up R&D," Briefing.com said in its note.
On vaccines, Bourla characterized recent policy shifts under US Health Secretary Robert Kennedy as misguided.
"Vaccines are an essential part of any health care system," Bourla said. "We will continue investing in vaccines because ... this is an anomaly that will correct itself. I hope pretty soon."
Under Kennedy, an appointee of Donald Trump, the Centers for Disease Control recently revised its website with language that undermines its previous, scientifically grounded position that immunizations do not cause autism.
Bourla has also touted a deal announced in September with the Trump administration in which the company promised to lower some drug prices in exchange for a three-year reprieve on planned tariffs.
Shares of Pfizer fell 3.8 percent in afternoon trading.
R.Braegger--VB