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Man City chairman defiant over reported Premier League charges
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Trump rejects Iran proposal for deal to reopen Hormuz
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Germany ready to 'walk through fire' for Klopp, says Tah
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England's Cox says injured Buttler leaves 'big shoes to fill'
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At least 16 killed in Russian and Ukrainian strikes
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Ruthless Perpignan upset sloppy Bordeaux-Begles
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Powerful storm pummels US Northeast
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Deadly abbey attack feeds anti-Ukrainian sentiment in Poland
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Bangkok declares disaster after homes flooded, roads submerged by heavy rain
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Antonelli says he drove 'safety-first' on his worst weekend of season
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Norris calls for errant Colapinto to be banned for causing Baku crash
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Fernandez fights back to reach Singapore Open final
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Russell finds himself again and prepares to heap pressure on Antonelli
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Giant statue of Pope Leo XIV takes shape in Peru workshop
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South Korea hold nerve to win Asian Games basketball gold
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Ukraine crush holders Italy to reach first BJK Cup final
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Russell holds off Verstappen to claim imperious victory in Baku
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Pope celebrates giant Paris mass in landmark visit
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Russell holds off Verstappen to win Azerbaijan Grand Prix
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Germany selects Munich for Olympics host bid
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India's Kohli says 2027 ODI World Cup will be his last
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Sagnol sacked as Georgia boss after Nations League upset
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Huge crowds cheer Pope Leo along Champs-Elysees ahead of Paris mass
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Man City could face 'drastic' sanctions after reported guilty verdict: ex-chairman
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Putellas wants to bring 'winning culture and mentality' to London City
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Furious Fury says row between rival promoters could scupper Joshua bout
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Rare Italian opera returns to Moscow after nearly 120-year hiatus
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'Invincible' 223cm teen basketball player stars as China win bronze
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Pope to celebrate giant Paris mass after 'peace' appeal
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Tenth woman found dead in South Africa's string of killings
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Homes flooded, roads submerged: Bangkok declares disaster over heavy rains
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Japan schoolboy, 11, wins gold while empty seats blight Asian Games
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Ahead of Paris mass, pope urges life together in 'dignity and peace'
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Japan organisers 'not satisfied' as empty seats blight Asian Games
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Austria 'ghetto' language classes leave children to repeat school
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Canals full, roads submerged as Bangkok declares flood disaster
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S.African women runners arm themselves after string of killings
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China, US to open AI 'communication channel' after summit
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'I felt embarrassed': Japan eSports whizz-kid, 11, wins Games gold
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Nepal tunnel survivor wants to help post-flood rebuild
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Indonesia fires threatens critically-endangered orangutan: IUCN
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New China sprint star, 17, vows 'no limits' after Asian Games gold
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Bangkok declares flood disaster across city
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Japanese 11-year-old wins Asian Games eSports gold
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'World records not enough': North Korea weightlifters target Olympic gold rush
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TikTok agrees to teen limits in US settlement following Meta
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Iran proposes Hormuz plan, Trump reportedly refuses
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Venezuela's oil cradle pins hopes on US energy deals
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El Nino rewrites the menu in the world's top restaurants
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US, China buy time with trade truce as pressure builds
Tepid 2026 outlook dents Pfizer shares
Pfizer signaled Tuesday it expects a challenging 2026 as it invests in new products to offset declines in Covid-19 revenues while limiting shareholder payouts.
Shares of the big drugmaker fell sharply after it projected a dip in full-year adjusted profits per share on roughly flat revenues.
Pfizer expects 2026 revenues of between $59.5 billion and $62.5 billion, compared with $62 billion in 2025.
The pharma giant last month completed an acquisition of biotech firm Metsera, deepening its portfolio of products in the fast-growing market for weight loss drugs.
Pfizer has also identified oncology as a major growth area, while Chief Executive Albert Bourla insisted the company would continue to invest in vaccines in the face of recent controversial policies under the vaccine-skeptic Trump administration.
The drugmaker expects a drop of $1.5 billion in 2026 revenues tied to lower Covid-19 sales and the decline of another $1.5 billion from products experiencing a loss of exclusivity.
Pfizer has maintained a dividend but not undertaken share repurchases in 2025. Executives said they would continue to steer cash into development programs rather than stock repurchases.
"Obviously I would love to do share repurchases," Chief Financial Officer David Denton said on a conference call. "The reality is at this point in time, I think the best and highest use of capital is continued investment in business development."
Briefing.com said the results underscored Pfizer's "painful transition" out of the Covid-19 era.
The tepid outlook "indicates that earnings will likely remain stagnant or decline slightly as the company digests the Metsera deal and ramps up R&D," Briefing.com said in its note.
On vaccines, Bourla characterized recent policy shifts under US Health Secretary Robert Kennedy as misguided.
"Vaccines are an essential part of any health care system," Bourla said. "We will continue investing in vaccines because ... this is an anomaly that will correct itself. I hope pretty soon."
Under Kennedy, an appointee of Donald Trump, the Centers for Disease Control recently revised its website with language that undermines its previous, scientifically grounded position that immunizations do not cause autism.
Bourla has also touted a deal announced in September with the Trump administration in which the company promised to lower some drug prices in exchange for a three-year reprieve on planned tariffs.
Shares of Pfizer fell 3.8 percent in afternoon trading.
R.Braegger--VB