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American Nobel laureate in medicine hopes to illuminate the brain
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Tens of thousands expected in Paris for high school protests
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Trump approves firing squad for convicted US military base shooter
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AI borrowing binge rattles US markets
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Grappling with 'homework scams,' US universities shun AI detectors
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Young Canadians sue government over alleged climate failures
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Separatists win Quebec election in test for Canada PM
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White Sox down Guardians to take 2-0 series lead
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Leaders visit Pacific atoll at frontline of climate change
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NHL record-breaker Ovechkin says current season will be his last
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Yemen's Houthis claim striking Riyadh airport, other Saudi sites
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France roar back in Nations League as Italy beat Turkey
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Best-selling British author Jeffrey Archer dies aged 86
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Messi readies for final farewell in Argentina send-off
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Military plane crash kills 32 in Nigeria
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Esposito seals Italy win over Turkey in Nations League
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Olise powers France to win over Belgium in Nations League
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Russia downplays plague reports as Trump offers US help
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High-flying Blazy turns to birdlife at Chanel
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Trump says US moved bombers from UK base after 'threats'
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Riyadh's allies pledge troops as Yemen, Saudi Arabia attack Houthis
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Brazilian stocks surge to record after Bolsonaro election lead
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Clashes erupt outside Kosovo parliament over war crimes court
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Leaders to visit Pacific atoll at frontline of climate change
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Milan's Saelemaekers suffers ankle setback, faces lengthy spell out
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ICC gives more details about arrest warrants for Taliban ministers
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Rubio arrives in Iceland to push for greater US presence in Arctic
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Nigeria's Tinubu confirms 32 dead after military plane crash
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Putin allows Italy's UniCredit to sell part of Russian business
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'Reckless' AI firms can't control models, says whistleblower
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Djokovic into China Open final as Medvedev out for hitting fan with ball
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Switching on brain cells: the Nobel-winning science of optogenetics
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ICC unseals arrest warrants for Taliban education ministers
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Quebec votes as separatist surge poses test for Canada PM
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Modric hopes fans back Croatia against Spain after England shame
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Euro slides as concerns about French debt mount
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Bolsonaro rides right-wing surge into Brazil's election runoff
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Former Trump press secretary Leavitt joins Fox News
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Turkey blocks X account of British reporter
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Djokovic advances to China Open final as Medvedev out for hitting fan with ball
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Ukraine says using AI robot guns to shoot down new Russian drones
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Disgraced former US House speaker dies at 84
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At Oct 7 memorial, Netanyahu says will be no Hamas rule in Gaza
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Euro slides as worries about French debt grow
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Ukraine blames Russia for deadly sinking of Turkish ship in Black Sea
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US withdraws all bomber aircraft from UK airbase
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UN rights council slams Taliban's 'oppression' of women
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Drone hits Ethiopia IDP camp as fears grow of regional war
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Norway eyes partial ban of smart glasses
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US-German trio wins medicine Nobel for illuminating the brain
Markets mixed as US jobs data tempered by economy worries
Equities were mixed Wednesday as building optimism that the Federal Reserve will cut interest rates before the end of the year was offset by renewed worries about the US economy.
A below-forecast read on job openings Tuesday indicated the resilient labour market was showing signs of softening a day after a big downside miss on factory activity -- suggesting a long-running period of high inflation and borrowing costs was taking its toll.
Job vacancies fell far more than expected in April, to below 8.1 million, which Briefing.com said was the lowest level since 2021.
The figures come ahead of closely watched non-farm payrolls figures due Friday, which will provide a much clearer snapshot for the US central bank ahead of its policy decision next week.
Readings below forecasts have for some time been taken as a positive, because they were seen as pointing to an economy still in rude health but slowing enough to give the Fed room to start cutting rates -- known as a "Goldilocks" situation.
However, some investors are getting uncomfortable.
"Recent economic reports have reinforced the notion that investors are increasingly looking beyond the 'Goldilocks' narrative toward something a bit more consistent with the flagging trajectory of consumption," warned Ian Lyngen and Vail Hartman, of BMO Capital Markets.
"There is nothing to imply that the real economy is on the precipice of a recession... rather that a no-landing for the labour market appears less likely than it did during the first quarter.
"Goldilocks is edging toward the door, but has yet to leave the building."
Still, bets on a Fed rate cut before the end of the year picked up, with some eyeing September as the lift-off point.
"The evidence is accumulating that the Fed should begin easing," said Lazard strategist Ronald Temple.
All three main indexes on Wall Street pushed higher, and Asia largely tracked those gains in the morning but struggled in the afternoon.
Sydney, Seoul, Taipei, Manila and Wellington all enjoyed buying interest, though Hong Kong, Tokyo, Singapore, Shanghai, Bangkok and Jakarta were in the red.
Mumbai rose more than two percent after tanking Tuesday when it appeared that India's Prime Minister Narendra Modi would not win as big an election victory as expected.
Exit polls had suggested Monday he was on course for a landslide, but as votes were counted it emerged that he had lost his majority and would have to rule with a coalition.
London, Paris and Frankfurt also advanced as traders in the eurozone geared up for an expected rate cut by the European Central Bank later in the week.
Crude prices edged up after recent hefty losses as investors digest the OPEC+ alliance of major crude producers' decision to begin winding back output cuts from October and through next year.
The decision comes as observers fret over demand for the commodity as data suggests US stockpiles are rising, while China's economy is still struggling to get back on track owing to soft consumer activity and a battered property industry.
- Key figures around 0810 GMT -
Tokyo - Nikkei 225: DOWN 0.9 percent at 38,490.17 (close)
Hong Kong - Hang Seng Index: DOWN 0.1 percent at 18,424.96 (close)
Shanghai - Composite: DOWN 0.1 percent at 3,087.56 (close)
London - FTSE 100: UP 0.3 percent at 8,253.26
Dollar/yen: UP at 156.05 yen from 154.80 yen on Tuesday
Euro/dollar: DOWN at $1.0871 from $1.0883
Pound/dollar: UP at $1.2782 from $1.2772
Euro/pound: DOWN at 85.11 pence from 85.19 pence
West Texas Intermediate: UP 0.3 percent at $73.44 per barrel
Brent North Sea Crude: UP 0.2 percent at $77.70 per barrel
New York - Dow Jones: UP 0.4 at 38,711.29 points (close)
G.Haefliger--VB